InnoPreP™ Innovative Preparative Chromatography

InnoPreP™ is a unique industrial-scale preparative chromatography capability offered by Servier. For more than 35 years, we have employed chromatography in our development and Servier has become a leading authority in this industry standard approach for purification.

InnoPreP™ represents the next step in this journey. We have invested in a new 500 m2 dedicated area at our Normandy facility in France, which houses a new lab, high containment capabilities, and adds a continuous processing option using simulated moving bed (SMB) to our existing column-based batch chromatography and SFC equipment.


  • Reduce your time-to-market by getting into the clinic up to 3 months faster
  • Optimize the purity of your APIs and intermediates
  • Develop high potent compounds (HPAPIs) for oncology, down to OEB 5
  • Scale up small chromatography processes to industrial volumes
  • Get to your target molecule with a better understanding of your process


  • 500 m2 industrial-scale preparative chromatography area
  • Batch technology, continuous processing (SMB), and SFC
  • High containment to handle high potent compounds (OEB 5)
  • 35 years of preparative chromatography experience
  • Team of 10 internationally-renowned experts

Batch Technology


Continuous Processing

  • Intensified process with Simulated Moving Bed (SMB)
  • Greater yields from fewer starting materials reduces costs
  • Very efficient for racemic separation
  • Green technology – Supercritical CO2
  • Falling Film Evaporator recycles up to 90% of solvent

Available Capacities

Phase Kg / day Tons / year
Normal < 50 < 20
Reverse < 40 < 16
Chiral < 15 < 6